Free of charge

Insights and key facts

Bioassay management explained by experts.
Discover concise information on PLA 3.0 and related bioassay management topics. Get quick, reliable answers to keep you informed and focused on what matters.
Insights and key facts are part of our 'Learning through the seasons' campaign.

End-to-end bioassay management

Analysis. Operation. Development. Administration.
Insights into PLA 3.0 as your software for managing your bioassay needs.

Data analysis

Take control of your assay data with PLA 3.0. Achieve accurate, consistent, and compliant results with powerful analysis tools tailored for biological assays.

Method operation

Ensure reliable and efficient routine analysis with PLA 3.0. Standardize your workflows and  reduce errors by applying validated methods effortlessly.

Method development

Optimize your assay workflows  with PLA 3.0. Develop, refine, and validate analytical methods that ensure accuracy, reproducibility, and regulatory compliance.

Administration

Manage your bioassay environment with confidence. Control user access, maintain data integrity, and ensure compliance with PLA 3.0's powerful administrative features.
Stay tuned!
Our experts are currently preparing new insights for you.

From A to Z

Explore the many layers of PLA 3.0

Read up on the key terms and concepts in our Knowledge Center—each letter links to a detailed topic.

A

Add-ons

PLA 3.0 add-ons extend the functionality of the framework to include the analytical methods your users require and enable them to visualize, document, and report results.
B

Basic bioassay protocol

Lets you combine the results of multiple independent assay runs into reportable values. Organize complex methods, retest scenarios, and report several products in a single assay.
C

Confidentiality

Data confidentiality ensures that data is protected from unauthorized access and disclosure, and that personal privacy and proprietary information is protected.
D

Documents

PLA 3.0 securely stores all your data within electronic documents. Your data remains complete, accurate, and consistent throughout its life cycle, thus ensuring data integrity.
E

Equivalence margin development

Lets you utilize data of historic assays to develop and verify test systems and use these systems to apply them in new assay development.
F

Framework

The PLA 3.0 framework is responsible for the integrity and reliability of measurement data. It provides the features you need to achieve regulatory compliance such as access control, data integrity, security, validation, and traceability.
G

G

xxx
H

H

xxx
I

I-Chart

I-Charts monitor data such as measurements and regression parameters at regular intervals, with each data point within the chart representing a sample or an observation respectively. All charts generated by the Control Chart Package are I-Charts.
J

Japanese Pharmacopoeia

xxx
K

Knowledge Center

xxx
L

L

xxx
M

Monitoring

xxx
N

Navigator

The Navigator on the left side of the PLA 3.0 main window is your main tool for accessing and organizing your documents and folders.
O

Observation group ID

Each assay element has a unique observation group ID assigned, linking the assay element to its respective observation data in the data editors. To switch plate positions for your samples, simply reassign the respective assay elements to a different observation group ID.
P

Preparation schemes

Preparation schemes are your central tool for efficiently assigning settings to assay elements. Define doses and dimensions of your treatments once and use the setup for as many assay elements as you require. Entering redundant information is not necessary.
Q

Quantitative response assays

Let you calculate relative potencies of Test samples compared to a Standard sample. If you provide information on the stock solutions or raw materials, you can also determine absolute potencies based on several types of calculations.
R

Response data processing

Use response data processing to configure the processing of response data, for example, to subtract the absorbance of blank wells or to divide response values by the mean absorbance of maximum binding wells.
S

Security contexts

Let you implement your permission system and control who can perform which tasks on documents stored in particular folders or folder trees.
T

Templates

Let you simplify tasks, standardize processes, and improve data security. Define document structures and initial values for documents, and control who can view and edit document sections and individual elements within documents.
U

U

xxx
V

Visualization

xxx
W

WECO rules

Let you detect out-of-control or non-random conditions on control charts, based on deviations from the mean. They are also capable of detecting patterns or trends. For example, you can apply Nelson rule 3 to detect when six (or more) points in a row are continually increasing (or decreasing).
X

XLXS files

xxx
Y

Y

xxx
Z

Z

xxx

GAMP

xxx

21 CFR Part 11

xxx

xxx

xxx

Regulatory compliance aspects

xxx
xxx

Log in to read the full insight.

International Council for Harmonisation (ICH)

xxx
xxx

Potency assays

xxx

Content assays

xxx

Impurity assays

xxx